Lifestyle changes may help ease indigestion. Your doctor may recommend:
- Avoiding foods that trigger indigestion
- Eating five or six small meals a day instead of three large meals
- Reducing or eliminating the use of alcohol and caffeine
- Avoiding certain pain relievers, such as aspirin, ibuprofen and naproxen
- Finding alternatives for medications that trigger indigestion
- Controlling stress and anxiety
If your indigestion persists, medications may help. Over-the-counter antacids are generally the first choice. Other options include:
- Proton pump inhibitors (PPIs), which can reduce stomach acid. PPIs may be recommended if you experience heartburn along with indigestion.
- H-2-receptor antagonists (H2RAs), which also can reduce stomach acid.
- Prokinetics, which may be helpful if your stomach empties slowly.
- Antibiotics, if H. pylori bacteria are causing your indigestion.
- Antidepressants or anti-anxiety medications, which may ease the discomfort from indigestion by decreasing your sensation of pain.